On the top of this picture we see Broadway. On the bottom we see what is now Second Street. I do not know what the building on the corner of Fourth Avenue and Second Street.
The church on the corner (shown with a "7") is identified as a Lutheran Church.
On the corner of Third Avenue and Broadway (near the upper left) is a building shown with a "16." This is identified as "Farmers' Home, Frank Henter."

Fargo, North Dakota
Detail Map of Fargo in 1880